Detection of Blood-Borne Viruses among Blood Donors in Diyala Governorate during 2024
DOI:
https://doi.org/10.59675/M411Keywords:
Hepatitis B virus, Hepatitis C virus, human immunodeficiency, ELISA, epidemiologyAbstract
Blood-borne viruses are viruses that some people carry in their blood and can be spread from one person to another. Those infected with blood-borne viruses may show little or no symptoms of serious disease, but other infected people may be severely ill. A screening test is done to detect potential health disorders or diseases in people who do not have any symptoms of disease. The goal is early detection and lifestyle changes or surveillance, to reduce the risk of disease, or to detect it early enough to treat it most effectively. Aim: To determine the blood viral infection among blood donation in Diyala governorate during 2024. Methods: Cross sectional study was conducted in the Blood Bunk in Baqubah Teaching Hospital during the period from January to December 2024 in Diyala Governorate. A seroepidemiologic survey about hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection using Elisa for qualitative detection for each virus. Results: The rate of blood viral infection among blood donation was 2.45% during 2024. High percentages of HBV 2.31% (662 cases) were noticed in this study followed by HCV and HIV 0.08% (25 cases) and 0.04% (14 cases) respectively. Infection in males more than females, and most positive cases were reported in age group 31-45 years 356 (53.78%) for HBV, 15(60%) for HCV, and 6 (42.85%) for HIV. There were differences in patient accommodations between Baqubah and its surrounding areas for each virus. Hepatitis B virus cases are distributed consistently throughout the year, with the highest prevalence in March 89(13.44%) and May 78(11.78%). Hepatitis C virus shows a relatively stable low prevalence across months, peaking slightly on January 5(20%) and August 5(20%). Human immunodeficiency virus cases remain consistently rare, with minor spikes on August 6(42.86%) and October 2(14.30%). Conclusion: Proportion of viral infection among blood donation was still high, further studies are recommended to follow up the rate of infection.
References
Flichman DM, Blejer JL, Livellara BI, Re VE, Bartoli S, Bustos JA, et al. Prevalence and trends of markers of hepatitis B virus, hepatitis C virus and human immunodeficiency virus in Argentine blood donors. BMC Infect Dis. 2014; 14:218.
Zaheer H, Saeed U, Waheed Y, Karimi S, Waheed U. Prevalence and trends of hepatitis B, hepatitis C and human immunodeficiency viruses among blood donors in Islamabad, Pakistan, 2005–2013. J Blood Disord Transfus. 2014; 5:217.
Walter SR, Thein HH, Amin J, Gidding HF, Ward K, Law MG, et al. Trends in mortality after diagnosis of hepatitis B or C infection, 1992–2006. J Hepatol. 2011;54(5):879–886.
Andrade AF, Oliveira-Silva M, Silva SG, Motta IJ, Bonvicino CR. Seroprevalence of hepatitis B and C virus markers among blood donors in Rio de Janeiro, Brazil, 1998–2005. Mem Inst Oswaldo Cruz. 2006;101(6):673–676.
Uneke CJ, Ogbu O, Inyama PU, Anyanwu GI, Njoku MO, Idoko JH. Prevalence of hepatitis B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria. Mem Inst Oswaldo Cruz. 2005;100(1):13–16.
Lavanya V, Viswanathan T, Malar SAS, Malarvizhi A, Moorthy K. Prevalence of hepatitis B virus infection among blood donors with antibodies to hepatitis B core antigen. Int J Med Med Sci. 2012;4(6):128–137.
Kafi-Abad SA, Rezvan H, Abolghasemi H, Talebian A. Prevalence and trends of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus among blood donors in Iran, 2004–2007. Transfusion. 2009;49(10):2214–2220.
Vogt M, Lang T, Frösner G, Klingler C, Sendl AF, Zeller A, et al. Prevalence and clinical outcome of hepatitis C infection in children who underwent cardiac surgery before the implementation of blood-donor screening. N Engl J Med. 1999;341(12):866–870.
Gurol E, Saban C, Oral O, Cigdem A, Armagan A. Trends in hepatitis B and hepatitis C virus among blood donors over 16 years in Turkey. Eur J Epidemiol. 2006;21(4):299–305.
Mast EE, Margolis HS, Fiore AE, Brink EW, Goldstein ST, Wang SA, et al. A comprehensive immunisation strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2005;54(RR-16):1–31.
Liang X, Bi S, Yang W, Wang L, Cui G, Cui F, et al. Epidemiological serosurvey of hepatitis B in China: declining HBV prevalence due to hepatitis B vaccination. Vaccine. 2009;27(47):6550–6557.
Liang X, Bi S, Yang W, Wang L, Cui G, Cui F, et al. Evaluation of the impact of hepatitis B vaccination among children born during 1992–2005 in China. J Infect Dis. 2009;200(1):39–47.
Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B virus infection: epidemiology and vaccination. Epidemiol Rev. 2006; 28:112–125.
Moore MS, Bocour A, Tran OC, Qiao B, Schymura MJ, Laraque F, et al. Effect of hepatocellular carcinoma on mortality among individuals with hepatitis B or hepatitis C infection in New York City, 2001–2012. Open Forum Infect Dis. 2018;5(2): ofy016.
Jung G, Olivas P, Díaz A, Lens S. Hepatitis E-induced acute-on-chronic liver failure and VI nerve paralysis. Liver Int. 2018;38(9):1696–1697.
Kadhim SJ, Kadhim NJ, Ali MR, Ogaili RH, Wahid Saleh YA, Mohammed RQ. Hepatitis B and Hepatitis C virus prevalence among Iraqi blood donors. Microbes & Infectious Diseases. 2025 Nov 1;6(4).
Mohammed KAS, Hameed MM, Mousa AH, Saleh AT. Prevalence and trends of transfusion-transmissible infections among blood donors in Basra, Iraq. BMJ Open Gastroenterol. 2023;10:e000968.
Hussein NR. Risk factors of hepatitis B virus infection among blood donors in Duhok City, Kurdistan Region, Iraq. Caspian J Intern Med. 2018;9(1):22–26.
Ali HE, Hussein AA, Hadi LM. Association between HBV, HCV, HIV and ABO blood groups among blood donors in Baqubah City, Iraq. Indian J Forensic Med Toxicol. 2021;15(3):4680–4687.
Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J. Harrison's principles of internal medicine. 20th ed. New York: McGraw-Hill; 2018. p. 360.
Tarky AM, Akram W, Al-Naaimi AS, Omer AR. Epidemiology of viral hepatitis B and C in Iraq: a national survey 2005–2006. Zanco J Med Sci. 2013;17(1):370–380.
Hussein AA, Motib AS, Hadi LM. Evaluation of ELISA and HBsAg rapid test cassette assay in detection of hepatitis B virus. J Pharm Sci Res. 2018;10(12):3157–3159.
Al-Rubaye A, Tariq Z, Alrubaiy L. Prevalence of hepatitis B seromarkers and hepatitis C antibodies in blood donors in Basra, Iraq. BMJ Open Gastroenterol. 2016;3(1):e000067.
Mo PY, Jin F, Li D, Zou W, Zhong J, Tong Z, et al. Prevalence and molecular characteristics of occult hepatitis B virus infection among blood donors in Huzhou City, eastern China. Gene. 2024; 927:148718.
AL-Mahdawi FK, Mohammed MR, Mahmood MM. Screening tests for voluntarily donated blood in Diyala governorate. InAIP Conference Proceedings 2022 Oct 25 (Vol. 2398, No. 1, p. 040030). AIP Publishing LLC.
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